cysteine protease — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T10924	Cysteine protease inhibitor-2		Cysteine Protease
	Cysteine protease inhibitor 2 is a cysteine protease inhibitor. Cysteine protease inhibitor 2 inhibited DCT116 and PC3 cells with GI50 values of 6.5 μM and 4.4 μM, respectively.		Cysteine Protease
T10925	Cysteine Protease inhibitor		Others
	Cysteine protease inhibitors are inhibitors of cysteine proteases. Target: Cysteine Protease		Others
T10925L	Cysteine Protease inhibitor hydrochloride	Cysteine Protease inhibitor hydrochloride (921625-62-9 free base)	Others
	Cysteine Protease inhibitor hydrochloride is a cysteine protease inhibitor.		Others
T79277	Cysteine protease inhibitor-3		Parasite
	Cysteine protease inhibitor-3 (Compound 15), a cysteine protease inhibitor, exhibits anti-plasmodial activity, effectively inhibiting Pf3D7 (IC50 = 0.74 μM), PfW2 (IC50 = 1.05 μM), PfFP2 (IC50 = 3.5 μM), and PfFP3 (IC50 ...		Parasite
T7451	2-Cyanopyrimidine	2-cyano-Pyrimidine	Cysteine Protease
	2-Cyanopyrimidine (m-Hydroxyphenylpropionic acid) is inhibitor of cathepsin K(IC50 : 170 nM)		Cysteine Protease
T6037	E-64	Proteinase inhibitor E 64,E 64,E64	Cysteine Protease , Antibacterial , Autophagy
	E-64 (Proteinase inhibitor E 64) is an irreversible and specific cysteine protease inhibitor. The IC50 of E-64 for papain is 9 nM.		Cysteine Protease , Antibacterial , Autophagy
T5211	NSC 185058	NSC185058	Cysteine Protease , Autophagy
	NSC 185058 is an inhibitor of ATG4B, a major cysteine protease. It also can attenuate the autophagic activity.		Cysteine Protease , Autophagy
T2470	MDL-28170	Calpain Inhibitor III	Cysteine Protease , Proteasome
	MDL-28170 (Calpain Inhibitor III) is a Cysteine protease.		Cysteine Protease , Proteasome
T19503	Papain		Others , Cysteine Protease
	Papain is a cysteine protease of the peptidase C1 family. Papain is used in food, pharmaceutical, textile, and cosmetic industries.		Others , Cysteine Protease
T15641	K777	APC-3316	P450 , Cysteine Protease , CCR
	K777 is a potent, orally active and irreversible inhibitor of cysteine protease. K777 is a potent CYP3A4 inhibitor (IC50= 60 nM). K777 is also a selective CCR4 antagonist featuring the potent chemotaxis inhibition. K777 ...		P450 , Cysteine Protease , CCR
T16809	Rupintrivir	AG-7088,AG7088,Rupintrivirvr	Virus Protease , Antiviral
	Rupintrivirvr (AG7088) is a selective rhinovirus (HRV) 3C cysteine protease mimetic peptide inhibitor with antiviral and immunomodulatory activities.Rupintrivirvr inhibits the replication of EV71 and EV-D68, and may be u...		Virus Protease , Antiviral
T20626	Esomeprazole		Proton pump , Cysteine Protease
	Esomeprazole is the S-isomer of omeprazole, inhibits the lysosomal cysteine protease legumain to prevent cancer metastasis. Esomeprazole is a proton pump inhibitors (PPI).		Proton pump , Cysteine Protease
T6040	Aloxistatin	E64d,Loxistatin,E64c ethyl ester	SARS-CoV , Cysteine Protease
	Aloxistatin (E64d) is an inhibitor of cysteine protease with blood platelet aggregation inhibiting activity. Aloxistatin is an irreversible, membrane-permeable inhibitor of lysosomal and cytosolic cysteine proteases with...		SARS-CoV , Cysteine Protease
T6738	Z-FA-FMK		SARS-CoV , Cysteine Protease
	Z-FA-FMK can irreversibly inhibit cysteine protease and also inhibit effector caspases.		SARS-CoV , Cysteine Protease
T6573	E 64c	NSC 694279,EP 475,Loxistatin Acid	SARS-CoV , Cysteine Protease
	E 64c (EP 475) , a derivative of E-64, is an irreversible and membrane-permeant cysteine protease inhibitor.		SARS-CoV , Cysteine Protease
T9458	PF-00835231		SARS-CoV
	PF-00835231 is a CoV-2 cysteine 3C-like protease (3CLpro) inhibitor, with IC50s of 0.27 nM and 4 nM for SARS CoV-2 and SARS CoV-1 3CLpro, respectively.PF-00835231 is the active compound of the first anti-3CLpro regimen i...		SARS-CoV
T36352	Suc-Leu-Tyr-AMC
	Suc-Leu-Tyr-AMC is a fluorescent substrate for calpain I and II and papain (another cysteine protease) that is used for measuring the chymotrypsin-like peptidase activity of the 20S proteasome (excitation max: 360 nm; em...
T77525	EN450		NF-κB
	EN450 is a cysteine-responsive covalent molecular gel degrader of targeted NF-κB with antiproliferative and potentially anticancer activity, which acts through a dependence on Cullin E3 ligase and protease, and can be us...		NF-κB
T2768	Saikosaponin A		NF-κB , Antibacterial , Liver X Receptor
	Saikosaponin A has a variety of pharmacological benefits, including antiepileptic, anti-osteoporosis, antioxidant, anti-in ammatory, immunomodulatory, and anti-bacterial activities. It can effectively attenuate neuropath...		NF-κB , Antibacterial , Liver X Receptor
T3161L	BACE-IN-1 acetate	BACE-IN-1 acetate (350228-37-4，Free base)	BACE
	BACE-IN-1 acetate (BACE-IN-1 acetate (350228-37-4，Free base)) has been used as β-site amyloid precursor protein (APP) cleaving enzyme-1 (BACE1) inhibitor in BACE1 inhibitor assay. β-Site amyloid precursor protein (APP) c...		BACE